LC-MS Instrumentation Engineer

Are you an experienced LC-MS instrumentation engineer looking to work with some of the most advanced analytical technologies in the industry?

We're looking for a LC-MS Instrumentation Engineer to be the technical expert for our liquid chromatography-mass spectrometry (LC-MS/MS) platforms, ensuring the reliability, performance and compliance of critical analytical instrumentation that supports world-leading scientific research and testing.

This is a rare opportunity to join a multidisciplinary scientific organisation where you'll work with cutting-edge Waters, Agilent and Thermo Fisher Scientific equipment, playing a key role in maintaining and developing one of the UK's leading analytical laboratory capabilities.

You'll be responsible for troubleshooting complex issues, driving continuous improvement, supporting laboratory teams and helping shape future instrumentation investments. You'll also provide support across adjacent technologies including GC-MS and IC-MS systems where required.

What You'll Be Doing

• You'll be responsible for ensuring the optimal performance, reliability and compliance of LC-MS/MS systems across our laboratories.
• Act as the subject matter expert for LC-MS/MS instrumentation, supporting a wide range of scientific programmes and analytical services.
• Troubleshoot, maintain, repair and qualify Waters, Agilent and Thermo LC-MS platforms to maximise uptime and laboratory productivity.
• Diagnose complex hardware, software and system integration issues, implementing effective solutions that minimise operational disruption.
• Support and maintain associated chromatography systems, including GC-MS/MS and IC-MS/MS instrumentation.
• Work collaboratively with scientists, laboratory managers, quality teams and external service providers to coordinate maintenance and improvement activities.
• Ensure instrumentation remains compliant with quality, regulatory and data integrity requirements.
• Identify opportunities to optimise instrument performance, improve workflows and increase laboratory efficiency.
• Support equipment lifecycle management, providing technical input into future instrumentation investment and laboratory development projects.
• Deliver technical training and mentoring, helping to build capability across scientific teams.
• Champion best practice in analytical instrumentation management, maintenance and continuous improvement.

What We're Looking For

We're particularly interested in candidates with substantial hands-on experience supporting LC-MS instrumentation within regulated laboratory environments.

You'll ideally have

• A degree in Chemistry, Analytical Chemistry, Engineering, Instrumentation, Biomedical Science or a related discipline, or equivalent industry experience.
• Extensive experience maintaining, troubleshooting and repairing LC-MS/MS instrumentation.
• Strong experience with Waters, Agilent and/or Thermo Fisher Scientific LC-MS platforms.
• A detailed understanding of mass spectrometry principles, liquid chromatography systems and associated instrumentation.
• Experience working in analytical laboratories supporting regulated testing or research activities.
• An understanding of instrument qualification, compliance, quality systems and data integrity requirements.
• Excellent communication skills and the ability to work effectively with scientists, operational teams and external suppliers.
• A proactive mindset with a passion for solving technical challenges and driving innovation.